INSIGHTS INTO TARGETING LKB1 IN TUMORIGENESIS

Insights into targeting LKB1 in tumorigenesis

Genetic alterations to serine-threonine kinase 11 (STK11) have been implicated in Peutz-Jeghers syndrome and tumorigenesis.Further exploration of the context-specific roles Bags of liver kinase B1 (LKB1; encoded by STK11) observed that it regulates AMP-activated protein kinase (AMPK) and AMPK-related kinases.Given that both migration and proliferat

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Awake thoracic epidural anaesthesia for laparotomy: A safer alternative to general anaesthesia in asthmatic patients

Asthma is a common obstructive lung disease with Bags a hallmark of airway inflammation and hyper-reactivity in response to a variety of stimuli.The morbidity and mortality in asthma is directly related to reversible airway obstruction and bronchospasm in response to specific triggers.The goal of the anaesthetist is to avoid eliciting triggering st

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Pressure of Societal Commitment Norm in Iran

Abstract Societal commitment involves sympathy and emotional Face Moisturizer attachment of actors to society and implies preference for public interest over self-interest.Secondary analysis of the Iranian Social Integration survey data shows that 64.6% of Iranians are socially committed and whenever faced with a dilemma of collective vs.self, they

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